Two Simple, precise, accurate and economical UV methods have been developed and validated for the quantitative estimation of cefdinir in bulk and pharmaceutical dosage form. Cefdinir has the absorbance maxima at 286 nm in methanol: distilled water (20:80). In the Method A, first order derivative spectra, cefdinir showed absorbance maxima at 273 nm and method B involved solving simultaneous equations based on measurement of area under curve at wavelength range 284-288 nm. The linearity for cefdinir was in the range of 5-50 μg/ml. The developed methods were validated according to ICH guidelines and were found to be accurate, economic and precise. The proposed methods can be successfully applied for the estimation of Cefdinir in bulk and pharmaceutical dosage forms.
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